Working and treatment of Valaciclovir - Valtrex Prescription drug
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| Working and treatment of
Valaciclovir - Valtrex |
Valacyclovir is an effective drug used in the treatment of viral
infections. It helps the body to fight against the infections that
are the caused of virus. These infections cause the virus to
multiply. This drug prevents this multiplication. When the drug is
used to treat genital herpes it acts differently. In this case its
main function is to avoid the virus from spreading to other person
and also prevents the outbreaks from recurring.
Valacyclovir is very easily and speedily converted to the active
form. This takes place by the hepatic metabolism called the
acyclovir. Acyclovir is than converted to its monophosphate form.
This process takes place due to thymidine kinase. a potent inhibitor
of viral DNA is the aciclo-GTP.It has 100 times more efficiency and
affinity to virus than the cellular polymerase. This state also
results into chain termination. This in turn is converted to its
triphoshate form due to the cellular enzymes.
This is the form that plays the main role. Acyclovir triphosphate
inhibits the viral DNA synthesis and thus prevents the viral
infections. This drug has greater oral bio availability which is
about 60% as compared to acyclovir which is only 10% to
20%.Valaciclovir does not kill the virus by itself. It prevents the
further growth of it. If lower numbers of virus are produced the
body’s immune system is able to overcome the viral infections
easily. The herpes zoster is treated by lessening the healing
process, alleviates pain and also other chronic problems. The drug
is more suitable for patients suffering form this trouble and having
age more than 50 years.
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